Salvia microstegia Merikarplarının Antimikrobiyal ve Antibiyofilm Aktiviteleri Üzerine Bir Araştırma

Abstract Biofilm-associated infections cause important health problems all over the world. Because of resistance to antimicrobials and their possible side effects, researchers' attention has been focused on plant extracts components. The aim this study is evaluate antimicrobial antibiofilm potentials Salvia microstegia Boiss. et Bal. mericarps. activity ethanolic extract obtained from mericarps was evaluated using microdilution method against seven standard bacteria three yeast strains. In addition, effect inhibiting biofilm formation preformed Pseudomonas aeruginosa determined crystal violet method. used showed moderate low tested yeasts with minimum inhibitory concentration (MIC) values ranging 62.5 250 µg/mL. Moreover, extract's potential inhibit biofilms found be greater compared its formation. conclusion, potential, however, additional studies involving different strains are needed reveal in a more holistic perspective.